Mitochondrial origin of membrane-associated heterogeneous RNA in HeLa cells.
نویسندگان
چکیده
منابع مشابه
A membrane-associated RNA of cytoplasmic origin in HeLa cells.
The genetic evidence of the existence in yeast' and molds2 of cytoplasmic determinants controlling the structure and function of mitochondria and the demonstration that mitochondria from all organisms contain DNA3-7 have indicated that transcription and translation processes dependent on cytoplasmic genes occur in eukaryotic cells. More recent observations in Neurospora have suggested that a cy...
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Heterogeneous nuclear RNA from HeLa cells contains double-stranded regions that arise by base pairing of complementary sequences that exist as parts of the same molecule (intramolecular base pairing). When denatured, the RNA sequences that form the double-stranded regions hybridize rapidly to HeLa cell DNA, suggesting that they are transcribed from reiterated sites in the genome. The messenger ...
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Interphase HeLa cells manifest a stepwise shutoff of RNA synthesis when the tonicity of the extracellular medium is gradually increased. Synthesis of heterogeneous nuclear RNA is most sensitive and is selectively inhibited at 1.5 times isotonicity (450 milliosmols/liter), while 45S ribosomal RNA synthesis is not affected significantly below 2.0 times isotonicity. Transfer RNA synthesis is least...
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The mode of mitochondrial formation has been so far directly investigated only in Neurospora crassa. By using a choline-requMng mutant of this organism, Luck (1963, 1965) has obtained evidence which strongly suggests that mitochondria are formed by growth and division of preexisting mitochondria. In Tetrahymena pyriformis (Parsons and Rustad, 1968), the distribution of long-term [aH]thymidine-l...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1968
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.61.1.261